CNS depression: Symptoms, risks, and treatment
Δ-opioid agonists can produce respiratory depression at very high doses; at lower doses, they have the opposite effect. High doses of a δ-opioid agonist can cause seizures, although not all delta agonists produce this effect.144 Activation of the delta receptor is usually stimulating instead of sedating like most opioids. In contrast, stimulants, or “uppers”, increase … CNS depression: Symptoms, risks, and treatment